Cimetidine and theophylline drug interaction
WebFeb 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours for three days (AX then aminophylline (200 mg) and cimetidine (300 mg) were administered every six hours for seven days (A-CX Multiple … WebThere are 7 disease interactions with theophylline which include: PUD renal dysfunction seizure disorders GERD hemodialysis reduced clearance tachyarrhythmias Report …
Cimetidine and theophylline drug interaction
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WebJan 11, 2024 · Coadministration with drugs that decrease theophylline clearance (eg, cimetidine, ciprofloxacin, and erythromycin and other macrolides): 0.2-0.3 mg/kg/hr IV or orally (extended release) ... Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this drug, tell your doctor or pharmacist of all the … WebAug 25, 2024 · Severe interactions of cimetidine include: astemizole; cisapride; dofetilide; eliglustat; lomitapide; pimozide; terfenadine; Cimetidine has serious interactions with at …
WebMay 8, 2024 · Warfarin's hepatic metabolism and protein binding are the most common mechanisms for the occurrence of drug-drug interactions. Warfarin is metabolized via the cytochrome P450 system by CYP 2C9, 1A2, and 3A4. It is a racemic mixture, with the S-enantiomer being 2.7 to 3.8 times more potent than the R-enantiomer. WebThe effects of cimetidine (1 g/day) on theophylline disposition and metabolism were examined in smokers and non-smokers for single dose intravenous and chronic oral administration of theophylline. In the intravenous study the effect of cimetidine on plasma theophylline clearance was more marked in smokers (22.7% reduction) than in non …
WebThe effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was …
WebTheophylline is used to treat lung diseases such as asthma and COPD ( bronchitis, emphysema ). It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to a ...
WebAfter intravenous administration of cimetidine, the majority of the parent drug (58-77%) is eliminated unchanged in the urine. 2,7 Cimetidine’s primary metabolite is cimetidine sulfoxide and represents an estimated … small shopify storesWebTheophylline; Warfarin; This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine. small shopping baskets with wheelsWebCimetidine-theophylline interaction: effects of age and cimetidine dose. Influences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. … hightec greaseguardWebDrug Interactions Cytochrome P450 Inhibition Strong and Moderate Inhibitors of CYP3A4 or CYP2D6 The effects of ketoconazole (a strong inhibitor of CYP3A4) at 400 mg once daily for 5 days on the pharmacokinetics of a single tamsulosin hydrochloride capsule 0.4 mg dose was investigated in 24 healthy volunteers (age range 23 to 47 years). small shopping bags for womenWebDec 13, 2012 · Clinically important interactions are predominantly manifested in those drugs which have a narrow therapeutic index (e.g. Phenytoin, warfarin, theophylline). The interaction leads to higher steady-state blood concentrations and hence increases the incidence of side effects and toxicity. Adverse effects of such interactions can be … hightec lijmWebCimetidine, 1,200 mg/day, significantly decreased theophylline clearance by 36% (range, 22% to 49%) and increased the mean elimination half-life from 5.7 hours … highteanWebWebMD provides information about interactions between THSC Cimetidine Oral and cimetidine-theophylline-derivatives. hightec make e 206 : 文件名或扩展名太长。