Cisplatin stock solution
WebCisplatin is a potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent … WebStock solutions of cisplatin and wedelolactone were made and stored at −20°C. 1mM solution of cisplatin was made (0.00150 g/5 mL) by dissolving powder in DMF followed by mQ water (1:4). 10mM solution of wedelolactone was prepared by dissolving 1 mg/0.32 mL of DMSO. ... The stock solutions were serially diluted with freshly prepared RPMI-1640 ...
Cisplatin stock solution
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WebCAS. 62996-74. Molecular weight. 466.54. Staurosporine is widely used as a positive control for inducing apoptosis. It has been proven that Staurosporine induces apoptosis in human malignant glioma cell lines, and arrests normal cells at the G1 checkpoint. Staurosporine is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum ... WebMar 9, 2024 · Aliquot the solution and store at −20 °C until use. Prepare the combination chemotherapeutics (combo) consisting of crizotinib plus cisplatin as follows: dissolve 5 mg of crizotinib in 1 mL solvent solution containing 25 μL of cisplatin stock solution to obtain a final concentration of 5 mg/mL crizotinib and 0.025 mg/mL cisplatin.
WebThe solubility of cisplatin in 0.9% NaCl is relatively low. The concentration of the stock solution is better less then 1 mg/ml (more preferably =0.5 mg/ml). Moreover, the … WebPreparing Stock Solutions for Doxorubicin hydrochloride The following data is based on the product molecular weight 579.99. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
WebMay 1, 1997 · Solutions stored in culture medium at -20 degrees C retained full cytotoxic potency. Conclusions: Cisplatin is a potent cytotoxic drug in vitro when stored under appropriate conditions. These findings are of relevance for in vitro studies with cisplatin. Publication types Research Support, Non-U.S. Gov't MeSH terms WebNov 10, 2011 · The effect of chemotherapy drugs (cisplatin, docetaxel, etoposide, and ARN-509) on VCaP and LNCaP spheroids was examined following the protocol described earlier for MLN. Drug stock solutions...
WebSep 15, 2024 · DESCRIPTION. Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL …
WebSep 29, 2000 · The original cisplatin solution (0.5 mg/mL) (ASTA Medica Frankfurt, Germany) was used to prepare a stock solution (0.1 mg/mL) in cell culture medium … shoffners automotiveWebJul 2, 2013 · The stability of cisplatin hydrochloride standard stock solution in a mixture of 1.4 mg/mL of OPDA solution, phosphate buffer pH 6.8, and DMF at a concentration of 0.8 μ g/mL was investigated at different time intervals using the experimental conditions. 2.2.3. Validation of the Developed Method (1) Linearity and Range. shoffner-kalthoffWebJul 7, 2014 · Cisplatin (cis-[PtCl2(NH3)2]), carboplatin ([Pt(O,O'-cdbca)(NH3)2], cbdca = cyclobutane-1,1-dicarboxylate) and oxaliplatin ([Pt(R,R-cyclohexane-1,2-diamine)(O,O′ … shoffr bangaloreWebMay 12, 2015 · Thought cisplatin can dissolve in DMSO and DMF, it can react with DMSO and DMF, forming adducts. It seems that cisplatin is stable in 0.9%NaCl solution, however, I get the information that... shoffstall construction llcWebSep 19, 2016 · Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy . For research … shoffstall constructionWebCisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Synonym … shoffnerkalthoff mes incWebJan 1, 1980 · It has been reported that cisplatin is unstable in solutions containing less than 0.9% sodium chloride and that the instability of cisplatin is increased by the presence of dextrose. It presents the stability data of cisplatin in aqueous solutions of dextrose, mannitol, sodium bicarbonate, and sodium chloride. shoffs polaris in rome ny