Gpx4 antibody cst
WebJul 22, 2014 · Intracellular localization of butyrate-induced GPx4 expression in VSMC. VSMC untreated (A) or treated (B) with 5 mM butyrate for different periods of time were processed for immunostaining of GPx4 with an antibody specific to GPx4 followed by Alexa flour 488 conjugated second antibody, as described in the Experimental Section. (400× ... WebProteintech Anti-GPX4 Polyclonal, Catalog # 14432-1-AP. Tested in Western Blot (WB) and Immunoprecipitation (IP) applications. This antibody reacts with Human, Mouse, Rat …
Gpx4 antibody cst
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WebGlutathione peroxidase 4 (GPX4) is a selenocysteine-containing glutathione peroxidase that is encoded by the GPX4 gene in humans and protects cellular membranes from oxidative damage.1,2 It is a monomeric protein consisting of a thioredoxin motif and a selenocysteine-glutamine-tryptophan catalytic triad that reduces lipid hydroperoxides ... WebPenicillin and streptomycin double antibodies were purchased from Genview. Cell Proliferation and Activity Assay Kit (CCK-8) was obtained from Shanghai Best-Bio. The primary antibodies PTPN18, GPX4, xCT and GAPDH were purchased from ABclonal. The primary antibody p-p38 was provided by Cell Signaling Technology and p38 was …
WebNov 12, 2024 · CST1 relieves GPX4 ubiquitination modification by recruiting OTUB1, improving GPX4 protein stability and reducing intracellular reactive oxygen species (ROS), thereby inhibiting ferroptosis... WebJun 18, 2024 · Glutathione peroxidase 4 (Gpx4) is a key enzyme in suppressing ferroptosis by reducing phospholipid hydroperoxides in membranes.
WebPolyclonal Antibody for studying GPX4. Cited in 8 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, GPX4 Antibody (CST … WebCell Signaling GPX4 Antibody ; CSIG-52455S. Cell Signaling GPX4 Antibody - CSIG (Additional S&H or Hazmat Fees May Apply) List Price $296.00 Your Price $296.00. …
WebJan 20, 2024 · Here, we firstly reveal that GPX4 regulated mitochondria-mediated apoptosis through regulation of EGR1 in TNBC cells. Compound 13, the prodrug of DMOCPTL, effectively inhibited the growth of breast tumor and prolonged the lifespan of mice in vivo, and no obvious toxicity was observed. Conclusions
WebApr 7, 2024 · Priming murine HNSCC with the ferroptosis inducer sensitizes tumors to anti-PD-L1 antibody treatment. A positive correlation between the ferroptosis signature and the active immune cell profile is shown in the HNSCC samples. ... Further analysis by TIMER 2.0 demonstrated that GPX4 expression was negatively correlated with the level of CD8 … how to set focus macros for healerWebSep 1, 2015 · GPx4 was visualized in whole zebrafish embryos by indirect immunofluorescence using a primary antibody against C-terminus of human GPx4 (Schoenmakers et al., 2010, Huang et al., 2009).This antibody could potentially recognize both predicted zebrafish GPx4 proteins a and b because the amino acid sequence of the … how to set fn keys as primary keyWebGPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about … note in the staffWebJan 11, 2024 · Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. how to set focus mode in outlookWebDec 31, 2024 · Glutathione peroxidase 4 (GPX4)-dependent ferroptosis in pancreatic acinar cells plays a critical role in acute pancreatitis (AP). However, potential upstream regulators of GPX4 are not well defined. Here, we observed a marked reduction in acinar GPX4 expression and ferroptotic cell death in mice with cerulein-induced AP. To determine the … note info markdownWebRabbit GPX4 Rabbit pAb (A13309), validaed in WB,IF/ICC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. … note in the pocket incWebAntibodies Anti-GPX4 Antibody Products Anti-GPX4 Antibody Products from Cell Signaling Technology There are over 300 anti-GPX4 antibodies from over 30 different suppliers shown below. You can also read 1 review from a researcher who performed Flow Cytometry on Human CD4 T cells. how to set focus on iphone