WebHigh-throughput systematic evolution of ligands by exponential enrichment (HT-SELEX) is a development of SELEX which uses next generation sequencing to analyse the aptamer selection process. Computational tools have previously been developed specifically to analyse HT-SELEX data and assist in shortlisting aptamers most likely to have high ... WebJan 27, 2024 · Whereas HT-SELEX used randomized DNA sequences as input, SNP-SELEX used a library of 40-bp DNA matching the reference human genomic sequence, …
FSBC: fast string-based clustering for HT-SELEX data BMC Bioinforma…
WebMar 15, 2016 · Analyzing HT-SELEX data with the Galaxy Project tools--A web based bioinformatics platform for biomedical research Methods. 2016 Mar 15;97: ... and transcriptome HTS data, and we have now applied these tools to aptamer HTS data. The Galaxy Project's public webserver is an open source collection of bioinformatics tools … WebApr 5, 2016 · HT-SELEX, which combines SELEX with high throughput sequencing, has recently transformed aptamer development and has opened the field to even more applications. HT-SELEX is capable of generating over half a billion data points, challenging computational scientists with the task of identifying aptamer properties such as sequence … pottery barn king of prussia store hours
Conservation of transcription factor binding specificities ... - eLife
WebLarge scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery. Novel in-silico methods to analyze HT-SELEX data are developed and utilized to study … WebThe HTPSELEX database contains sets of invitro selected transcription factor binding site sequences obtained with SELEX and high-throughput SELEX method. The database … WebApr 11, 2024 · PDF On Apr 11, 2024, Saurabh Chaudhary and others published Comprehending testes-specific gene regulation in Drosophila melanogaster Find, read and cite all the research you need on ResearchGate pottery barn kinley vanity