網頁DOI: 10.1016/j.immuni.2024.02.004 Corpus ID: 257554479 ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING. @article{Fang2024ARMH3mediatedRO, title={ARMH3-mediated recruitment of ... 網頁2024年10月24日 · transmembrane protein, mediates innate immune activation upon cGAMP stimulation and is ... Mechanistically, RAB22A engages PI4K2A to generate PI4P that recruits the Atg12 –Atg5–Atg16L1 complex ...
Viruses Free Full-Text Tissue-Resident Innate and Innate-Like …
網頁2014年1月27日 · The development of new and effective adjuvants may play a fundamental role in improving HIV vaccine efficacy. New classes of vaccine adjuvants activate innate immunity receptors, notably toll like receptors (TLRs). Adjuvants targeting the C-Type lectin receptor DC-SIGN may be alternative or complementary to adjuvants based on TRL … 網頁2024年10月14日 · Guanylate binding protein 5 (GBP5) belongs to the GTPase subfamily, which is mainly induced by interferon gamma (IFN-γ) and is involved in many important cellular processes, including inflammasome activation and innate immunity against a wide variety of microbial pathogens. However, it is unknown wh … topachat 3080
我国学者在天然免疫的细胞信号转导领域取得进展 - 生物通
網頁The triggering of innate immune mechanisms is emerging as a crucial component of major neurodegenerative diseases. Microglia and other cell types in the brain can be activated in response to misfolded proteins or aberrantly localized nucleic acids. This diverts microglia from their physiological and … 網頁2024年10月26日 · Many factors determine whether an individual responding to vaccination will generate an immune response that can lead to protection. Several studies have shown that the pre-vaccination immune state is associated with the antibody response to vaccines. However, the generalizability and mechanisms that underlie this association remain … 網頁2024年4月6日 · Other innate immune stimuli were used to treat RAW264.7 CD63-pHluorin cells, and the sEV release rates were upregulated by IFN-β-related ligand treatment (Figure S5a). The distributions of PI4P and MVBs changed in a manner similar to the change observed after LPS treatment (Figure S5b ). pick up c10 a vendre